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It was identified during pharmacokinetic investigations of MT-2 as the primary active metabolite formed following in-vivo hydrolysis of the MT-2 acetyl cap, resulting in a free N-terminal amine in place of the N-acetyl group

Exp Gerontol 2003

Physiologically relevant doses of lactate have been shown to rescue the oscillatory shear stress (OSS)-induced decrease in GPR81 expression, reduce oxidative stress, and inhibit OSS-induced endothelial inflammation by activating Kruppel-like factor 2 (KLF2) expression, which may prevent the development of atherosclerosis (69)

This simple step prevents the introduction of bacteria and other contaminants