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Dihexa was administered orally via gavage at doses of 1.25 mg/kg or 2.0 mg/kg, 25 minutes before behavioral testing

Symptoms associated with partial biotinidase deficiency can be similar to those of the profound deficiency form but often these symptoms do not appear as severe except during infections, illnesses, or stress

Glutathione pathways NAC, glycine, selenium, zinc, vitamin C or vitamin E may be considered according to antioxidant demand and tolerance

For instance, a high incidence of mild stomach upset has been observed in a clinical trial of -cyclodextrin inclusion of SFN ( in vivo studies as well as safety evaluations of these delivery systems will greatly promote the translational research of SFN from bench to bedside