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A physician can also evaluate fatigue, weakness, hormone concerns, thyroid issues, and nutrient status when needed

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- In the Triumph-4 Phase III trial involving adults with obesity and knee osteoarthritis, participants receiving the highest dose of retatrutide lost an average of 28.7% of their body weight over 68 weeks, and experienced a 75.8% decrease in pain scores associated with osteoarthritis-related knee pain