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These changes increased intracellular accumulation of ECM proteins and decreased secretion into the extracellular environment, indicating impaired protein trafficking and secretion

The incidence of [metabolic dysfunction-associated steatotic liver disease (MASLD)] is rising, and it is projected to be a leading cause of liver transplantation in the US, study author Charanpreet Sasan, MD, told GI & Hepatology News in advance of Digestive Disease Week (DDW) 2026, where the work was presented