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Moreover, in models of ischemiareperfusion injury and in KEAP1-inactivated lung cancer, inhibition or genetic ablation of CoQ biosynthetic enzymes restored sensitivity to ferroptosis or radiotherapy 115,116 , underscoring the reliance of some cancer cells on an abundant CoQ pool for redox defense and survival

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This gender difference could be attributed to the lower muscle mass in females than males, making them prone to muscle cramps following cirrhotic sarcopenia [14]

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