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Loss of angiotensin II receptor expression in dopamine neurons in parkinsons disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation

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Conclusions Unstable iron deposits within cells lead to an unbalanced redox state, causing a type of cell death known as ferroptosis which differs from other types of death