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doi:10.1056/NEJMcp1113996 2Socha DS, DeSouza SI, Flagg A, Sekeres M, Rogers HJ

Improved Insulin Sensitivity Fourth, NNMT inhibition improves insulin sensitivity and glucose metabolism through multiple mechanisms including increased NAD+ and SIRT1 activity, reduced adipose tissue inflammation, and improved mitochondrial function

Also, if you went heavy on B vitamins, that could be contributing

Vitamin B12 deficiency can cause significant neurological impairment, stressing the importance of early diagnosis and treatment. Forms of B12: Why Methylcobalamin Matters for Nerve Pain Methylcobalamin is the best B12 for nerve pain