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The body aches sometimes reported on tirzepatide and the anxiety some users experience do not appear to be more common on retatrutide, suggesting these effects are GLP-1/GIP mediated rather than glucagon-dependent
However, there is no evidence that any of these medications reduce the risk of diabetes-related complications, cardiovascular mortality, or all-cause mortality
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Although the correlation between mtDNA mutation and male infertility has been reported, the specific mechanism of the correlation needs to be further studied
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