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Yrekli Y, Unak P, Yenisey C, Ertay T, Biber Mftler FZ, Medine E

[2] Use of estradiol cypionate injection is contraindicated in individuals with undiagnosed abnormal vaginal bleeding, known or suspected breast cancer or other estrogen-dependent neoplasia, active or prior venous thromboembolism, recent arterial thrombo-occlusive disease such as stroke or myocardial infarction, severe hepatic impairment, a history of hypersensitivity to estradiol or any excipients, and in those who are or may become pregnant

Patients should never raise the dose on their own

Try warming the combination on the back of your hand and applying it with a flat makeup brush