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[119] fabricated a bilateral microneedle patch to deliver cyclodextrin-based metalorganic framework (CD-MOF)-encapsulated DXMS and paeonol to overcome the disadvantages of conventional intranasal administration, which not only enhanced the therapeutic effect of the drug but also reduced mast cell degranulation and modulated Th17/Treg cell homeostasis
If you are pregnant, breastfeeding, or taking medications, consult with your doctor before starting a supplement routine
Resveratrol, a polyphenolic stilbene, displays concentration-dependent biphasic actions, at low doses it can weakly mimic estrogenic effects via ER activation, whereas at higher pharmacologic concentrations it acts as an ER antagonist, inhibits aromatase transcription, and disrupts co-activator recruitment to the ER complex, thereby exerting anti-proliferative and pro-apoptotic effects in ER-positive breast cancer cells (192)
