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We hope the present review will provide inspiration for researchers to develop more drugs that modulate 7nAChR activity that produce the neuroprotective effect, not only for the treatment of ASD but also for ameliorating other neurological abnormalities by proposed new drug target for enhancing cholinergic neurotransmission

however, when rigorously designed using proven analytic approaches to emulate reference trials, real-world evidence of several glucose-lowering drug classes have demonstrated strong concordance with trial estimates 20,22,32

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