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What Remains Unknown, And What Research Is Underway We still lack large randomized trials designed to measure depression and other psychiatric outcomes as primary endpoints for Tirzepatide

Weight loss can markedly reduce disease severity, and the recent TGA approval of tirzepatide for obstructive sleep apnoea in adults with obesity offers a novel adjunct to continuous positive airway pressure, broadening treatment strategies and improving long-term health outcomes

Additionally, studies have reported potential mild, transient increases in serum cortisol levels, particularly at higher doses

This blog post will predict key issues faced by plaintiffs pursuing claims in the ongoing multidistrict litigation against manufacturers of these drugs, and will argue that courts should recognize an exception to the learned intermediary doctrine for GLP-1 RA drugs