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During activation, T cells use glycolysis to metabolise glucose despite the presence of oxygen, a procedure called aerobic glycolysis, which is critical for the efficient secretion of cytokines such as IFN- and IL-2.29-31 One marker for aerobic glycolysis is the rapid consumption of glucose in the culture medium because aerobic glycolysis is less efficient in producing adenosine triphosphate (ATP) compared with oxidative glycolysis

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Because the heart relies almost exclusively on fatty acid oxidation for its massive energy needs, carnitine supplementation also provides vital cardiovascular and autonomic support, which is particularly relevant for patients managing the complex symptoms of Postural Orthostatic Tachycardia Syndrome (POTS): Cardiovascular Strain: By ensuring a steady supply of long-chain fatty acids to the cardiac mitochondria, L-carnitine supports healthy heart muscle function and improves the heart's ability to pump efficiently under stress