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Treated wounds contracted at least 11% more than controls by day 7, with increased collagen deposition and angiogenesis confirmed histologically

385,387 PF1801 displays its anti-inflammatory effects by lowering levels of inflammatory mediators such as TNF, IL-6, and HMGB1, and enhances the cells antioxidant capability by upregulating molecules like Nfe2l2, Hmox1, Gclm, and Nqo1, which further improves cellular defense against oxidative stress and protects them from further damage

Role of leptin and adiponectin in insulin resistance