This meta-analysis showed that, over 398 patients with schizophrenia treated with antipsychotic followed up between 12 and 24 weeks, the GLP-1RAs liraglutide and exenatide were superior to placebo for body weight, waist circumference, BMI and blood pressure 134
While rare, more serious side effects such as pancreatitis or thyroid issues can occur
Oral tirzepatide absorption is slower than injection, but sustains therapeutic levels longer due to extended half-life in sublingual tissue beds
Here, it tweaks the balance of neural signals, releases satiety signals, suppresses hunger, cuts down on the desire to eat, controls calorie intake from the source, and helps stabilize blood glucose in a reasonable range