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Ye X, Tam WL, Shibue T, Kaygusuz Y, Reinhardt F, Ng Eaton E, et al

Tesamoreline (TH9507) 44 amino acids with an N-terminal trans-3-hexenoic modification

These studies provide mechanistic plausibility for the relationship between urolithin A and sleep health through direct and indirect mechanisms such as modulation of the central clock, protection against neuroinflammation caused by sleep deprivation, and modulation of the gut microbiota