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The main concern involves effect stacking rather than a documented drug conflict

Ongoing Clinical Trials Numerous questions remain under investigation, including: Long-term biological effects Extended safety profiles Pharmacodynamic characteristics Receptor-level adaptations Combination therapy applications As a result, ongoing clinical trials continue to generate new information regarding the compounds biological activity and potential future applications

For patients with localized, completely resected, low-grade tumors, prognosis is more favorable, and long-term survival is possible

By discussing the practical challenges, clinical feasibility and workflow integration of these biomarkers, the present review aims to bridge the gap between basic mechanistic research and clinical application