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74 Fibroblast growth factor 21 (FGF21) also contributes to MASLD pathogenesis

The table shows that resmetirom is a small (molecular weight about 600 g/mol), non-iodinated THR- agonist administered once daily as an oral tablet, while semaglutide is a large (about 4 kDa) GLP-1 peptide designed for once-weekly subcutaneous injection or, with SNAC enhancement, once-daily oral administration

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However, variations in liver efficiency and enzyme activity among individuals mean that some people may metabolize alcohol more quickly or slowly than others, leading to differences in BAC levels after consuming the same amount of alcohol