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CAS Registry Number: 910463-68-2

Importantly, tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

The medical community increasingly recognizes that obesity treatment often requires long-term pharmacological intervention, similar to managing other chronic diseases

A recent market survey (see Table 1) estimated that only 34% of first-time Wegovy prior authorizations under CVS were approved ( [46] ) ( [4] ) (implying a 66% denial rate on initial submission)