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Escalation is not automatic: it requires an explicit go-ahead from the SRC against these pre-agreed criteria

In the aforementioned study from our group, adult mice with partial IGF-1 also displayed decreased expression of genes involved in lipid metabolism (ATP-citrate lyase, acetyl-CoA acyltransferase 1B, acetyl-CoA acetyltransferase 1) and cholesterol synthesis and transport (Both HMG-CoA reductase and synthase, LDL-related protein 1, proprotein convertase subtilisin/Kesin type 9), resulting in dyslipidaemia

These examples collectively highlight the pervasive, yet often overlooked, presence of hormetic effects within the food we consume, emphasizing the need for a nuanced understanding of dose-response relationships in the context of food and health

Progress slows without explanation