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The dataset was partitioned randomly into training (70% of the sample) and held out test (30%) sets, with the test set being used to assess model performance

To view digital features for this article go to Introduction Obesity (defined as a body mass index [BMI] 30 kg/m 2 in adults [1]) is a major health concern in the USA [2] and is associated with multiple complications, including cardiovascular disease, type 2 diabetes, and osteoarthritis [3,4,5,6,7,8]

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Several case reports indicate that the concurrent use of GLP-1RAs and dipeptidyl peptidase-IV inhibitors (DPP-4Is) might elevate the risk of developing specific cancers, such as breast, thyroid, and pancreatic cancers [124]