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Dosage and Route: Take oral capsule(s) by mouth on an empty stomach and as directed by your prescriber

Peripheral inflammatory signals and energy deficits may impact brain tissue through multiple pathways, activating microglial cells and astrocytes, disrupting neuronal metabolism and synaptic transmission, and thereby potentially contributing to the neurological phenotype of PEM

To confirm that GH activates AgRP neurons, whole-cell patch-clamp recordings were performed in brain slices of AgRP-reporter mouse (Supplementary Fig

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