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Common side effects were predominantly gastrointestinal, including nausea, diarrhea, constipation, and vomiting, primarily during dose escalation [45] [46]

Injecting semaglutide in the evening and eating a light breakfast the next morning often results in less nausea than injecting earlier in the day

So in general, there is a very nice effect, good effect on the vascular system, and of course, the vascular system is common for the entire body, so the kidneys and the liver and the heart and what have you, everything, also the brain