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It acknowledges that this is a systemic endocrine-metabolic disorder, not just an ovarian problem, which should improve communication between patients and clinicians

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These are actually the same receptors that the alpha agonists guanfacine and clonidine act on, however instead of activating these receptors, mirtazapine blocks or deactivates these same receptors

While hiccups are generally benign and self-limiting, persistent episodes lasting more than 48 hours warrant medical evaluation to rule out other causes