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Stem Cells Int 2016:7954580 Asahara T et al (1999) VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

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Multiple animal studies including post-infarction models show Thymosin Beta-4 reduces scar tissue formation, promotes cardiomyocyte survival, and supports microvascular regeneration in damaged heart tissue.22 A 2010 study published in Annals of the New York Academy of Sciences showed that Thymosin Beta-4 initiated adult cardiac progenitor cell differentiation and cardiac repair in injured myocardium.23 While direct long COVID RCT data doesn't yet exist for TB-500, the mechanistic overlap with long COVID cardiovascular pathology is strong