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Tributyrin is a triglyceride (fat) form of butyric acid, which the company and published material suggest may be more targeted in delivery than sodium butyrate - a more common but odorous and potentially less colon-specific butyrate supplement form

A 2024 pilot in interstitial cystitis and a 2021 case series in knee pain reported it as well-tolerated within those small samples

Some direct-to-consumer health companies are exploring the use of peptides, such as growth hormone secretagogues like MK677, to modulate the immune system and improve lymphocyte to monocyte ratios, with some individuals showing significant improvements in their ratios after treatment 5m6s

2014 Nov 20;9(11):e110598