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Escalating to 15 mg when you only need to lose 10 more pounds puts you in a position where the step-down later is steeper and more likely to cause rebound weight gain

Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial

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