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You should not take either drug if you: Are under the age of 18 Are pregnant, breastfeeding, or planning to become pregnant Have kidney or liver disease Have a known allergy to either medication Additionally, both Zepbound and Ozempic carry a black box warning about an increased risk for thyroid C-cell tumors because these drugs caused thyroid tumors in rats in studies

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Elderly Patients: Hypoglycemia and weight gain are common problems in elderly diabetics receiving insulin or sulfonylureas, especially when the class of medications powerfully affects glucose

Cancer 50 , 24562462 (2014)