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Patients experiencing persistent vomiting or diarrhoea should maintain adequate hydration and contact their GP if symptoms are severe or prolonged, as dehydration can complicate diabetes management

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2, with the early phase being the consequence of potential indirect mechanisms, followed by a later phase of direct stimulation, when gut contents have travelled to distal parts of the intestines) have not accumulated much evidence in favour of a biphasic GLP-1 response in human participants

Semaglutide remains a clinically validated, effective GLP-1 agonist