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Ensuring efficacy, safety, and durability comparable to injectable GLP-1 RAs while minimizing adverse effects, particularly gastrointestinal discomfort, is essential

Moreover, the concentration of carnitines in biological samples is low, and complex sample preparation steps are needed to improve the sensitivity of the detection method, which however increases the analysis time

Muz 1 1 Marqus de Valdecilla Health Research Institute (IDIVAL), Cefaleas y otras enfermedades neurolgicas no degenerativas, Santander, Spain The Journal of Headache and Pain 2026 , 27(S1): P595 Objective CGRP, mainly a-CGRP, is central in migraine pathophysiology, whereas -CGRP is more prevalent in the gut