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Likewise, restraint stress rapidly modulated KP enzyme expression in rats, with amygdala IDO increasing within 1 h, amygdala KMO and kynureninase rising by 4 h, hippocampal TDO decreasing within 4 h, hypothalamic TDO upregulated at 4 h, and medial prefrontal cortex kynureninase reduced shortly after stress with effects lasting at least 24 h [70]

Abstract Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central nervous system that also act in the pancreas as peripheral regulators of metabolism

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320 In addition to muscular manifestations, Duchenne muscular dystrophy is often associated with psychosocial abnormalities and cognitive impairment, while histopathologically neuronal death and dendritic abnormalities are frequently observed post-mortem