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The ratio of melanocytes to keratinocytes in the basal cell layer of the oral epithelium, measured linearly, ranges from 1:10 to 1:15 [17]

Additionally, AhR signaling can alter microbial composition in the small intestine, acting as a crucial regulator of host-microbiota communication, thereby affecting host metabolism and modulating the immune system [54,55,56,57,58]