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Understanding the mechanisms of -syn spread, as well as the impact of peripheral pathology on disease progression, is essential for the purpose of developing effective diagnostic and therapeutic strategies for PD

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In people with the familial form, signs and symptoms often recur on a regular basis and may return during times of stress, such as during illness or pregnancy

Nevertheless, precise identification of vascular GLP-1R + cell types linked to the reduction of atherosclerosis following treatment with GLP-1RA remains uncertain (9)