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DiNicolantonio JJ, Niazi AK, McCarty MF, Lavie CJ, Liberopoulos E, OKeefe JH, MedReviews LLC (2014) L-carnitine for the treatment of acute myocardial infarction

In the pivotal SURPASS clinical trial program evaluating tirzepatide for type 2 diabetes, arthralgia was documented as an adverse event, but occurred at similar rates in both tirzepatide and comparator groups, suggesting it may not be directly attributable to the medication itself

However, persistent injection site reactions caused the trial to pause temporarily

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