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Why it matters: Injecting a contaminated medication can cause local infections (at the injection site), systemic infections (bacteremia, sepsis), or life-threatening conditions

It has also been reported that catalase is an important enzyme implicated in mutagenesis and inflammation conditions as well as during the suppression of apoptosis [1518] which are all known to be associated with oxidative stress conditions

CVDs are among the most concerning complications of HU, with numerous studies linking high UA levels to an increased risk of coronary artery disease, hypertension, metabolic syndrome (MS), and stroke

doi: 10.3390/ijms21197152 64 Birnie-GauvinKPeimanKSLarsenMHAarestrupKWillmoreWGCookeSJ