glp 1 ckd benefit Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists GLP-1 Receptor Agonists and Diabetic

Acting as an MC4R agonist, it has been shown to promote satiety, reduce caloric intake, and support weight loss

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A recent study found that gut bacterial metabolite, Ruminococcaceae isoamylamine (IAA), which is enriched in older adults and aged mice, promotes age-related cognitive dysfunction by promoting microglial cell death (Teng et al., 2022)

As such, its important that weight-loss medication is used as part of a broader approach to healthy weight management, including access to appropriate nutrition, physical activity and behavioural support. Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, said: Expanding the range of effective treatments is important in helping people sustainably reduce caloric intakes within an increasingly obesogenic environment