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Tirzepatide is a dual GLP-1R/GIPR agonist that co-activates both the GLP-1 receptor and the GIP receptor, enabling researchers to study the additive or synergistic effects of dual incretin co-activation in metabolic models
Our article on lyophilised peptide integrity in transport explains why storage and movement conditions form part of the wider quality picture
Eighty-six percent (86%) of ZEPBOUND-treated patients had a maximum tolerated dosage of 15 mg weekly based on their final dose during the double-blind treatment period
10.1038/nrendo.2017.151 Summary Keywords daphnetin, diabetes cognitive dysfunction, pharmacological effects, GLP-1 receptor, inflammation and oxidative stress Citation Liang F, Tian X and Ding L (2024) Daphnetin modulates GLP-1R to alleviate cognitive dysfunction in diabetes: implications for inflammation and oxidative stress
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