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The idea is that microdosing can: Reduce side effects: Its common to experience side effects when taking GLP-1s, especially gastrointestinal issues including nausea, vomiting, and diarrhea

Some protocols describe loading phases of higher doses followed by maintenance

In well designed, 24-week trials in treatmentnaive patients with type 2 diabetes mellitus, monotherapy with oral saxagliptin 2.5 or 5mg once daily significantly improved glycaemic control, as measured by mean glycosylated haemoglobin (HbA 1c ) levels, relative to placebo

Semaglutide might be a suitable option for adults with a Body Mass Index (BMI) of 30 or more (considered obese) or those with a BMI of 27 or more (considered overweight) who also have a weight-related health condition like type 2 diabetes