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Notably, PIEZO1 regulates RBC activity during blood storage, with subclinical channel activation leading to ion imbalance and microvesiculation

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22 However, epidemiological and clinical studies have linked hyperuricemia to the development of various conditions, including chronic kidney disease, fatty liver, metabolic syndrome, hypertension, insulin resistance, obesity, type 2 diabetes, and cardiovascular and cerebrovascular disorders

However, the applicability of this approach is often hindered by the low concentration and sporadic occurrence of mycotoxins, which results in a loss of statistical power