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How GLP-1 Medications Differ from Other Weight Loss Drugs: Traditional Weight Loss Medications: Stimulants (phentermine): Increase energy, suppress appetite through adrenaline-like effects Fat blockers (orlistat): Prevent fat absorption in intestines Combination pills (Contrave, Qsymia): Multiple mechanisms, moderate effectiveness These produce 3-9% average weight loss at best

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Further analyses revealed that changes in blood GSH were highly correlated with those in erythrocytes, and changes in lymphocyte GSH were significantly correlated with those in both blood and erythrocytes