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Subcutaneous administration once daily, particularly at bedtime, is designed to mimic physiological patterns of endogenous GH secretion [2] [3]

2.1.1 Senescence-associated secretory phenotypeSASP The senescence-associated secretory phenotype, also known as the senescence-messaging secretome, functions as a collection of proteins released by senescence cells into their microenvironment, serving as a key marker of cellular aging [32, 33]

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Journal of Pharmacology and Experimental Therapeutics, 344(2), 503ae'510