The above findings indicate that these DMSA monoesters are a superior treatment choice to DMSA in terms of inducing recovery from altered biochemical variables and causing the depletion of the lead burden in the body
They decrease inflammatory markers, lower LDL cholesterol and triglycerides, and have been shown to reduce major adverse cardiovascular events
In TRIUMPH-4, the higher-dose arms saw discontinuation due to side effects of around 12% to 18%, though some of that was linked to baseline weight and to perceived excessive weight loss rather than intolerance alone

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