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Adiponectin increases glucose absorption and fat burning in muscle and liver cells, and decreases glucose production in the liver (Yadav 2013)

It also enhanced insulin sensitivity, as evidenced by increased plasma insulin levels and decreased HOMA-IR values

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Graphical Abstract Keywords Insulin resistance, Lipid metabolism, Metabolic dysfunction-associated steatotic liver disease, MASLD, Oxidative stress, Silent information regulator 1, SIRT1, Therapeutic targeting Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver condition closely linked to metabolic abnormalities