semaglutide in kidney disease VisualAbstract: Improves Outcomes Patients with Type 2 Diabetes and Chronic can semaglutide cause kidney failure

Gastrointestinal Issues Around 15% to 20% of individuals using Ozempic experience nausea, the medications most frequent gastrointestinal side effect

High sugar content can trigger diarrhea through osmotic effects, while acidity may irritate the stomach lining and worsen nausea

Ocular Very common (10% or more): Diabetic retinopathy (up to 20.1%) Common (1% to 10%): Retinal disorders, diabetic retinopathy complications Uncommon (0.1% to 1%): Nonproliferative retinopathy Very rare (less than 0.01%): Nonarteritic anterior ischemic optic neuropathy (NAION) Diabetic retinopathy complications included need for retinal photocoagulation, need for treatment with intravitreal agents, vitreous hemorrhage, and onset of diabetes-related blindness

Semaglutides CV benefits are mediated through a combination of direct and indirect mechanisms