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Based on available evidence, SCFAs exert protective effects by activating the Nrf2/GPX4 pathway to inhibit lipid peroxidation, while LPS acts through the dual mechanisms of suppressing the antioxidant defense system (GPX4) and disrupting iron metabolic homeostasis

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5.2 Distribution into blood cells When determining blood concentrations of bioactive molecules, blood cells are usually disregarded and discarded after centrifugation to simplify analytical methods

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