LH increased nearly fourfold from baseline during infusion, with testosterone rising by approximately 45 percent

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Both candidates are designed to move beyond single-pathway GLP-1 therapy, but they take very different routes: CagriSema combines an amylin analog with semaglutide, while Retatrutide compresses GIP, GLP-1, and glucagon agonism into one investigational peptide
This way, healthcare providers can give better, more tailored care