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Situmorang et al., 2024

PMID: 25226827

For researchers designing protocols where physiological fidelity and established safety are priorities, sermorelin remains a defensible choice

the clinical significance in humans remains under investigation and is not yet established for retatrutide specifically [24] [25] Other class-associated cautions: Based on the broader GLP-1/GIP receptor agonist class, potential effects on gallbladder function and delayed gastric emptying are relevant considerations, though evidence specific to retatrutide is still emerging It is important to note that this evidence derives from early-phase trials conducted under controlled conditions with medical supervision