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Chongqing University #OpenAccess: To view or add a comment, sign in As the pace of #cancer innovation accelerates, it can be a lot to keep up with the many breakthroughs reshaping the treatment landscape

However, despite affinity, albeit lower, of tirzepatide for the GLP-1 receptor, tirzepatide had no effect on body weight, food intake, fasting insulin, endogenous glucose production and insulin-stimulated glucose uptake in skeletal muscle and subcutaneous white adipose tissue of GLP-1 receptor knockout mice [89]

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There was nothing that caused dramatic weight loss