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As loss of ATM correlates with decreased pigmentation in hair follicle melanocytes it is difficult to determine if loss of melanin contributes to a reduction in ATM expression or drives the process of ATM loss more rapidly

For most enzyme inducers, hyperplasia is transient and may require specific DNA labeling studies or immunohistochemical stains to clearly identify its occurrence

Gross-total resection (GTR) was the treatment of choice in all amenable cases, followed in selected cases with residual tumor by adjuvant radiotherapy or chemotherapy

The GLP1R rs6923761 variant influences GLP-1 receptor sensitivity, while the FTO rs9939609 variant correlates with appetite-regulation pathways