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Those with recurrent pancreatitis or severe gastroparesis may require dose adjustment or alternative approaches

First and foremost, it will be important to examine the potential mediating effects of weight loss and glucose-lowering on the effectiveness of different GLP-1RAs to understand both why we are seeing the observed benefits and why differences between drugs exist, they say

The selected studies involved 138,282 participants (mean age = 64.8 years, range 57.1 to 71.9 years